A Case of 
Cyclosporine-induced Reversible Parkinsonism

Keimyung Medical Journal 2001;20(1):84-86.

A Case of Cyclosporine-induced Reversible Parkinsonism

사이클로스포린에 의해 유발된 가역적 파킨슨증 1례

최종환; 이현아; 이형; 임정근; 이상도

Abstract

Cyclosporine A (CsA) widely used for immunosuppression has been associated with various neurologic side effects including postural tremor; seizure; headache; encephalopathy and Parkinsonism. However; there has been no report describing CsA induced Parkinsonism in Korea. We described a 41-year old woman with cyclosporine induced Parkinsonism characterized by bradykine- sia; cogwheel rigidity; postural and resting tremor. She had been received CsA for a few months to prevent rejection after renal transplantation. There were high signal intensities in both putamen; sub-thalamic and caudate nuclei on T2-weighted MRI. After discontinued CsA; her symptoms were disappeared.

Key Words: Parkinsonism, Cyclosporine A