A Case of
Dimethylformamide-induced Toxic Hepatitis |
디메틸포름아미드(dimethylformamide)에 의한 독성 간염 1례 |
정인성; 이충원 |
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Abstract |
Dimethylformamide is a solvent used extensively in the chemical industry. The effect of it’s exposure in human are not well documented. However; liver is the main organ afflicted after acute or chronic exposure. We report a patient with toxic hepatitis induced by dimethylformamide. His job was textile coating. He complained fatigue; alcohol intolerance; facial flushing and nausea. He had abnormally high serum aminotransferase level. The amount of urinary excretion of N-methylformamide was 300 ㎍/㎖. Possibilities of viral hepatitis; autoimmune hepatitis and alcoholic hepatitis were ruled out by his personal history and serological study. Liver function became normal after management for a month. |
Key Words:
Dimethylformamide, Toxic hepatitis |