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Keimyung Medical Journal 2013;32(2):178-182.
A Rare Case of Rathke Cleft Cyst with Xanthogranulomatous Change
라스케열낭종의 황색육아종성 변화 1례
A rare case of symptomatic Rathke cleft cyst (RCC) with xanthogranulomatous change is reported; which is discovered in a 16-year-old girl presenting with primary amenorrhea and no development of secondary sexual characteristics. The endocrinological assessment revealed the patient had a hypogonadotropic hypogonadism. Brain magnetic resonance imaging demonstrated a 17 mm sized cystic lesion with rim enhancement in the intra- and suprasellar region. Via an endonasal microscopic approach; the cyst was completely decompressed and the cyst wall was partly excised. The cyst contents were confirmed intraoperatively with distinct colors and consistencies. Pathological examination of surgical specimen showed a nonciliated columnar epithelial lesion associated with xanthogranulomatous changes. The author speculate that xanthogranulomas in the sellar region might be caused by reaction to the presence of RCC.
Key Words: Amenorrhea, Hypogonadism, Rathke cleft cyst
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