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Keimyung Medical Journal 1990;9(3):365-368.
A Case of Twenty-Nail Dystrophy Accompanied by Alopecia Universalis
전신 탈모증을 동반한 20조갑 이영양증 1례
김석주; 이원석; 박의수; 송준영
Abstract
We report a case of twenty-nail dystrophy accompanied by alopecia universalis in a 45-year old woman. She had developed dystrophic nail changes on her all finger and toe nails for 26 years and alopecia universalis for 10 years. On examination; 20 nails were affected with opalescent; thickening; longitudinal ridging; and total hair loss were in scalp; eyebrow; axilla; and pubic area. Mycologic study of involved nails was performed; but negative results were obtained. Histologic findings of dystrophic nails revealed prominent hyperkeratosis; acanthosis; and mild infiltration of mononuclear cells in the upper dermis. The histologic findings of scalp showed a few atrophic hair follicle; thining of epidermis; and slightly hyperkeratosis. All of these clinical and histologic findings were considered as twenty-nail dystrophy accompanied by alopecia universalis. She was treated with intralesional injection of triamcinolone acetonide and topical application of dinitrochloro- benzene; but no significant improvement was made. The further observation is being conducted.
Key Words: Alopecia universalis, Twenty-nail dystrophy
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