| Decreased Uptake in Bone Scan("Cold Lesions") in Metastatic Carcinoma |
| 약년(若年) 성인의 경골신경 체감각 유발전위의 정상치 및 자극빈도의 변동에 따른 유발전위의 변화 |
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김옥배; 김영훈; 최태진; 김홍; 김정식; 전석길; 우영훈 |
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| Abstract |
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Radionuclide bone scans have made possible early detection of a metastatic skeletal lesions. The expected abnormality in bone scan is positive or "hot" lesion indicating increased uptake of radiotracer. However "cold" lesions or false negative bone scans have also reported in metastatic carcinoma of bone.
In the past 4 years; we have observed a total of 14 cases who had positive radiographic findings but had "cold" spot or normal findings on radionuclide bone scans. Of the 14 patients; 3 had single “coid" spot; 10 had a single "cold" spot and "hot" spot(s) concurrently; and the remainder one had normal bone scan. The most common site of metastatic bone lesion as "cold" spot was spine; 8 cases. The primary site of cold bone metastasis were as followings; lung cancer 3; breast ca. 2; renal ca; 2; ovarian ca. 1; esophageal ca. 1; adrenal ca. 1; acute lymphoblastic leukemia 1; prostatic ca. 1;and unknown primary 2;
The recognition of a wide spectrum in bone scan images will give useful concept in the interpretation and understanding of bone scan
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