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Keimyung Medical Journal 1986;5(2):124-131.
Malate Dehydrogenase Activity in the Regenerating Rat Liver
흰쥐 재생간의 Malate Dehydrogenase의 활성치
김여희; 곽춘식; 문교철
A study was made on the changes in the activities of the following during 6 post-operative days: Cytosolic and mitochondrial malate dehydrogenase of regenerating rat livers, and rat serum nialate dehydrogenase after 70而 (median and left lateral ]ohes) partial hepatectomy. The activities of lactate dehydrogenase and alanine aminotransferase in both serum and cytosol of regenerating rat liver were also measured. After partial hepatectomy in the rats, activity of serum malate dehydrogenase tremendously increased in in the span between the 12 hours and the second day. The activity of cytoslic malate dehydrogenase in the regenerating liver significantly increased from the first to the second day after partial hepatectomy. However, no significant rhnnges in hepatic mitochondria] maiate dehydrogenase was noted throughout the experiments. The activities of scrum lactate dehydrogenase and alaiiiiio aminotranslerase milrkedly elevated after partial hepatectomy. And activity of h}hnine aminntrans("erase significantly decreased in the hepatic cytosol after partial hepntcctomy hut hepatic cytosolic lactate dehydrogenase showed no change.

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