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Keimyung Medical Journal 2013;32(2):205-208.
Rapidly Evolving Bilateral Ophthalmoplegia as an Initial Manifestation of Myasthenia
급격히 진행하는 양안의 안근 마비로 발현한 중증근무력증 환자
이창엽; 전지예; 이병찬; 이형; 임정근; 김현아
Myathenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatigue. Symptoms are caused by circulating antiboties that block acetylcholine receptor at the post synaptic neuromuscular juction; inhibiting the excitatory effects of the neurotransmitter acetylcholine on receptor. At early stage of myasthenia gravis; ptosis and diplopia are common symptoms. The ophthalmoplegia is a rare symptom of the early stage of myasthenia gravis. We described a 52-year-old female with myasthenia gravis; presenting with acute ophthalmoplegia. Within 3 weeks the patient was transferred to intensive care unit because of respiratory failure. Thus; we have to consider that acute ophthalmolegia can be the initial symptom of myasthenia gravis and disease course is rapidly deteriorated.
Key Words: Acute ophthalmoplegia, Myasthenia gravis
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