A Long-Term Survival Case of Primary Angiosarcoma
in Liver Treated with Weekly Docetaxel Chemotherapy

Keimyung Medical Journal 2011;30(2):183-190.

A Long-Term Survival Case of Primary Angiosarcoma in Liver Treated with Weekly Docetaxel Chemotherapy

Sun Kyung Park; Jin Young Kim; Jung Min Lee; Gang Guk Lee; Young Rok Do; Keon Uk Park; Hong Suk Song

Abstract

Angiosarcoma is rare malignant endothelial cell tumor of vascular or lymphatic origin. It may occur in any region of the body; but more frequent in skin and soft tissue. Though hepatic angiosarcoma is rare primary tumor of the liver; it is the third most common primary malignant tumor of the liver. Treatment options for hepatic angiosarcoma are limited; and they depend mainly on the stage of the disease during diagnosis. We report a rare case of primary angiosarcoma of the liver. We treated our patient with weekly docetaxel chemotherapy regimen. She received a total of six cycles without disease progression or unendurable toxicity occurred; and had long-term survival fourteen months after the diagnosis. An effective treatment for hepatic angiosarcoma has not yet been established. Chemotherapy with docetaxel should be considered in the treatment of patients with primary angiosarcoma of the liver.

Key Words: Angiosarcoma, Docetaxel, Liver