The Effect of Intravitreal Triamcinolone Acetonide or Avastin Injection According to the OCT
Patterns of Macular Edema |
황반부종형태에 따른 유리체 내 트리암시놀론 및 아바스틴 주입 효과 |
장지혜; 김유철; 김광수 |
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Abstract |
This study was aimed to compare clinical outcomes according to the morphologic patterns of
macular edema after a single intravitreal injection of triamcinolone acetonide (TA) or avastin for
the treatment of macular edema. One hundred and thirty-eight eyes with diabetic macular edema
(DME) or macular edema in branch retinal vein occlusion (BVOME) were enrolled in this study.
Macular edema was classified into four morphologic patterns based on optical coherence
tomography (OCT): Cystoid macular edema; sponge-like macular edema; serous macular
detachment; and combined macular edema. Visual acuity and central macular thickness (CMT)
were compared between the groups at 2 weeks; 1; 2 and 6 months after therapy. The combined
macular edema type in DME and BVOME patients showed better improvement of visual acuity and
foveal thickness. In aspect of the treatment for macular edema; the sponge-like macular edema
treated intravitreal TA injection revealed worst improvement of visual acuity. The significant
reductions of CMT were observed all types of macular edema after the procedure. There was no
significant difference about a recurrence of macular edema between the groups. This study
revealed that the pattern of macular edema using OCT will help to determine the anatomic and
functional effect of intravitreal injection. |
Key Words:
Intravitreal avastine injection, Intravitreal triamcinolone acetonide injection,
Macular edema type |