The Features of Second Primary Cancer after Diagnosis of Colon Cancer |
대장암 진단 후 발생된 이차성 원발암의 특징 |
이상민; 박선경; 이형기; 김주연; 김진영; 도영록; 박건욱; 송홍석 |
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Abstract |
Colon cancer is a major cause of cancer-related mortality in Western country; and
4th cause leading to cancer mortality in Korea. The occurrence of metachronous colon cancer
have increased; due primarily to improvements in diagnostic modalities; and increased survival
rate of colon cancer; and increased concern about occurrence of second cancer. It is important to
be aware of the clinical characteristics of double cancer in colon cancer patients for early
diagnosis and treatments. We describe our clinical experience of second primary cancer after
diagnosis of colon cancer. We reviewed the clinicopathologic data of 1;201 patients with colon
cancer; who had been diagnosed at Dongsan Medical Center from January 1996 to December
2007. Second primary cancer had occurred in 28 patients. There were 6 (21.5%) synchronous
and 22 (78.5%) metachronous cancer patients. Most common cancer was stomach cancer in 6
(21.4%) patients; and lung cancer and skin cancer in 3 (10.7%) patients respectively. Median
survival duration after the diagnosis of colon cancer was 65.0 months. The most common second
primary cancer was stomach cancer after the diagnosis of colon cancer. The present study
suggests that the follow up of colon cancer over 10 years is needed in order to enable the early
diagnosis of second primary cancers; and we should undergo upper gastrointestinal endoscopy
regularly for early detection of second cancer. |
Key Words:
Colon cancer, Metachronous, Second primary cancer, Synchronous |
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