Efficacy of intravenous clarithromycin therapy for mycoplasma pneumonia in children |
소아 마이코플라즈마 폐렴에서 clarithromycin 정주요법의 효능 |
김희운; 김유경; 유재성; 김명진; 송진영; 김문규; 강호석; 오세호; 이상은 |
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Abstract |
Intravenous clarithromycin therapy (ICT) for mycoplasma pneumonia in children
and adolescent is one of the effective treatment modality; but most of the comparison studies with
other modalities were done in adults. This study aimed to assess the characteristics and
effectiveness of ICT for mycoplasma pneumonia in children and adolescent. From March 2006 to
December 2007; 34 patients were treated with ICT and 71 patients with non-ICT; which were
considered to be control group. Preadmission characteristics and responsiveness were analyzed
retrospectively. The mean age of ICT and control group were 5.7 and 4.2 years old respectively.
And there was significant difference (p=0.005). The mean preadmission fever duration were 4.9
day in ICT group and 3.3 day in control group (p=0.04). No other preadmission parameters
showed statistically significant differences. Average fever duration after initiation of antibiotics in
ICT group was less than in control group(0.12 day vs. 0.61 day ; p=0.03); However there was no
statistically significant differences in duration of admission and readmission rate between two
groups. These results show that intravenous clarithromycin therapy may be a good choice for the
treatment of mycoplasma pneumonia in children and adolescent especially if the fever duration
was prolonged. |
Key Words:
Intravenous clarithromycin, Mycoplasma pneumonia, Prolonged fever |