Abrupt Onset Sheehan’s Syndrome with Acute Adrenal Insufficiency after Delivery

Keimyung Medical Journal 2008;27(1):69-73.

분만 직후 나타난 쉬한증후군으로 인한 급성 부신기능저하

김윤정; 김남경; 하유진; 김미경; 장영윤; 김혜순; 박근규

Abstract

Sheehan's syndrome is a postpartum hypopituitarism due to acute ischemic necrosis of the anterior pituitary gland secondary to severe postpartum bleeding and shock. Generally; it is diagnosed several months to years after the last delivery complicated with severe postpartum bleeding. However; we experienced a case of abrupt onset Sheehan's syndrome with acute adrenal insufficiency occurring 20 days after delivery with severe bleeding. Hormonal study revealed decreased cortisol and growth hormone response to insulin-induced hypoglycemia. The patient recovered dramatically with glucocorticoid replacement therapy.

Key Words: Acute adrenal insufficiency, Sheehan’s syndrome

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