Characteristics of diffusion-weighed imaging in patients with acute multiple brain infarction |
급성 다발성 뇌경색 환자에서 확산강조자기공명상의 유용성 |
정두교 |
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Abstract |
While we often observe acute multiple brain infarction (AMBI); their clinical
significance has not been fully investigated. We sought to determine the relationship between the
characteristics of AMBI in diffusion-weighted imaging (DWI) and internal carotid artery (ICA)
disease and middle cerebral artery (MCA) disease of unilateral AMBI in the anterior circulation.
We studied 107 consecutive ischemic stoke patients who underwent DWI and MRI/MR
angiography within 3 days of stroke onset. Patients were assigned to 1 of 5 observed lesion
characteristics in DWI: (1) multiple small lesions (<1 cm); (2) multiple small and medium lesions
(1 to 3cm); (3) multiple small and large lesions (>3 cm); (4) multiple lesions in hemodynamic risk
zone; and (5) others. The involvement of insula; periventricular white matter (PVWM); basal
ganglia; and cortex was also investigated. Comparisons of all these characteristics were made
between ICA disease patients (ICA group; n=43) and MCA disease patients (MCA group; n=64)
on MR angiography. There was no significant relationship between cerebral artery involvement
and the characteristics of lesions in DWI. Between 2 groups of arterial disease; maximum
diameter of lesion which is more than 3 cm and PVWM involvement were significantly related with
MCA group (p=0.02 and p=0.007). The pathogenic mechanisms of unilateral AMBI can be
predicted by the characteristic of its size and location using DWI. |
Key Words:
acute multiple brain infarction, diffusion-weighted imaging |