Hemolytic Uremic 
Syndrome Associated with Salmonella
Food Poisoning in Adult: A Case Report

Keimyung Medical Journal 2002;21(1):111-116.

Hemolytic Uremic Syndrome Associated with Salmonella Food Poisoning in Adult: A Case Report

Salmonella 식중독 후 발생된 성인 용혈성 요독 증후군 1례

강미정; 강민경; 성정훈; 한승엽; 박성배; 김현철

Abstract

The hemolytic uremic syndrome (HUS) is a rare disorder in adults. It usually occurs in association with various drugs; pregnancy; hypertension; malignancy and collagen vascular diseases. We report here a case of adult HUS caused by Salmonella infection in a 52-year-old male renal allograft recipient who received a kidney from a living-related donor four years ago. He developed nausea; vomiting; abdominal pain and watery diarrhea after dining out. During hospitalization; he developed microangiopathic hemolytic anemia; thrombocytopenia and a rapid rise of serum creatinine. Stool culture revealed Salmonella group B; and urine and blood cultures were sterile. He was treated with intravenous fluids and antibiotics. The patient recovered without plasma exchange. The onset of HUS concomitant with Salmonella food poisoning and the prompt reversion of the HUS after antibiotic treatment of the Salmonella enteritis suggests the causal relationship between HUS and Salmonella infection.

Key Words: Hemolytic uremic syndrome, Salmonella infection, Diarrhea