| Comparison of
Breast Conservation Procedure with Modified
Radical Mastectomy in Treatment of Breast Cancer |
| 유방암의 치료에 있어서 유방보존술과 변형근치유방절제술의 비교 |
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김대동; 손창용; 김진희; 김유사 |
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| Abstract |
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Modern prospective studies
have demonstrated that breast conservation
procedure (BCP) and modified radical mastectomy (MRM) produce comparable
actuarial survival rates. This study was designed to evaluate the merit of
BCP in the treatment of breast cancer. 134 patients underwent BCP during the
period of Aug. 1987 to Aug. 2000 (BCP group); and they were compared with
patients who underwent MRM during the same period (MRM group). Tumor size;
lymph node status and age were similar between the two groups. The clinicopathologic
features; locoregional recurrence; distant metastasis; actuarial overall
survival rate and disease-free survival rate were analyzed. The mean age of the
BCP group was 44.6 yrs; and that of the MRM group was 44.8 yrs. The mean size
of tumor was 1.89 cm in the BCP group and 1.92 cm in the MRM group. Among
the 134 patients in the BCP group; no lymph node metastasis was observed in 92
(68.7%); 1-3 lymph node(s) in 26 (19.4%); and more than 4 lymph nodes in 16
(11.9%). In the MRM group; the numbers were the same. In the BCP group; the
actuarial 5-yr overall survival rate was 88.20% and the 5-yr disease-free survival
rate was 84.2%. For the MRM group; the actuarial 5-yr overall survival rate was
85.7% and 5-yr disease-free survival rate was 80.4%; showing no significant difference
between two groups. Thirteen in the 134 BCP group and five in the 134
MRM group had locoregional recurrences and five in the 134 BCP group and 17 in the 134 MRM group had distant metastases. The above results suggest that BCP can be a
standard surgical treatment modality for most patients with early stage breast cancer. |
| Key Words:
Breast cancer,
Breast conservation therapy, Survival rate |
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