A Case of B-Cell
Prolymphocytic Leukemia |
B형 전림프구성 백혈병 1례 |
윤상미; 이홍석; 박근규; 전동석; 송홍석 |
|
|
Abstract |
Prolymphocytic leukemia (PLL)
first described by Galton and colleagues in 1975; is a distinct clinicopathologic variant of chronic lymphocytic leukemia. It is characterized by marked lymphocytosis; massive splenomegaly; minimal lymphadenopathy; and poorrognosis. The clinical course of PLL is generally brief; the median survival in Galton's original series was 4 months. We experienced a case of B-prolymphocytic leukemia. The patient was a 64 year-old man who presented with splenomegaly; marked leukocytosis and 65% of characteristic prolymphocytes in the peripheral blood. We report a case of PLL with a prolonged course after combination chemotherapy with daunorubicin; L-asparaginase; vincristine; prednisolone; and methotrexate. |
Key Words:
B-prolymphocytic leukemia, Combination chemotherapy
|
|