The Value of Bone Scintigraphy in the Rheumatic Arthritis

류마티스성 관절염에서 전신 골 스캔의 유용성

박재호; 류종걸; 김순; 전석길; 김정만

Abstract

Purpose : To evaluate prospectively the possibility of 99mTc-MDP bone scan to detect early involvement of peripheral joint in rheumatic arthritis. Materials and Methods : 588 joints in 42 patients with rheumatic arthritis; whole body bone scan with 99mTc-MDP and static bone scan of multiple joints of extremities(Wrist & Ankle) were done. Additionally; in 24 patients with positive rheumatic factor is compared. Results : The overall sensitivity and specificity of bone scan based on physical findings are 76.2% and 85.2%; respectively. The sensitivity and specificity of radiographic finding based on physical findings are 37. 6% and 84%; respectively. In 24 patients with positive rheumatic factor; the sensitivity and specificity of bone scan based on physical findings are 71.7% and 84%; respectively. The sensitivity and specificity of radiographic finding based on physical findings are 54.5% and 87.4% respectively. Conclusion : The bone scintigraphy is more sensitive than radiograph; may antedate the development of physical finding; regardness of positive rheumatic factor. We conclude that bone scintigraphy with 99mTc-MDP is a valuable tool in the prediction of early joint involvement and evaluation of rheumatic arthritic activity in rheumatic arthritis.

Key Words: 100mTc-MDP, Rheumatic arthritis, Whole body bone scan