Aspergillosis of Central Nervous System in Immunocompetent Host. |
Hyun Ah Kim, Hyera Jung, Ilman Kim, Seong Yeol Ryu |
1Department of Infectious Disease, Keimyung University School of Medicine, Daegu, Korea. 121rsy@dsmc.or.kr 2Department of Pathology, Keimyung University School of Medicine, Daegu, Korea. 3Department of Neurosurgery, Keimyung University School of Medicine, Daegu, Korea. |
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Abstract |
Aspergillosis of the central nervous system from sinonasal origin is rare in immunocompetent hosts. Due to the rarity of the cases in immunocompetent hosts, only few cases are reported in the previous literature. But, some cases reported diversity of clinical presentations in immunocompetent hosts. Aspergillosis of the central nervous system from sinonasal origin, bony invasion with only orbit or cranial base was more common than intracerebral aspergillosis in immunocompetent hosts. In this type of disease, although maxillary sinus is more commonly involved, sphenoid sinus and clivus are unusual sites for aspergillosis of central nervous system. Because of the anatomical position of sphenoid sinus, it is associated with poor prognosis with intracranial extension. We reported a case of the aspergillosis of central nervous system involving clivus in the immunocompetent host who was misdiagnosed as metastatic tumor or plasmacytoma due to the unusual location and host factor. |
Key Words:
Brain neoplasm, Immunocompetence, Neuroaspergillosis |
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