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Keimyung Medical Journal 2014;33(2):126-131.
Published online December 31, 2014.
A Case of Polyostotic Fibrous Dysplasia Masquerading as a Mulptile Bone Metastases.
Jaekyung Cheon, Yumun Jeong, Ji Young Yang, Sunpyo Lee, Misun Chung, Eun Mi Son, Jae Lyun Lee
1Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
2Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
4Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jaelyun@amc.seoul.kr
Abstract
Fibrous dysplasia is a benign, bony abnormality that is usually asymptomatic. A 41-year-old male with minimal symptoms presented at this hospital with abnormal findings incidentally seen in his ribs on the chest radiograph. A skeletal survey showed numerous, osteolytic lesions throughout multiple bones. Diagnostic processes for malignancy of undefined primary origin (MUO) were performed in order to identify the underlying primary neoplasm, although abnormal findings were not seen except for multiple bone lesions. A computed tomography guided bone biopsy was performed on his left rib. The final diagnosis was fibrous dysplasia. This case demonstrates that fibrous dysplasia should be considered in the differential diagnosis in young patients with multiple, osteolytic lesions and without a prior history suggesting malignancy.
Key Words: Bone neoplasm, Fibrous dysplasia, Metastasis
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