Disseminated Herpes
 Zoster in Patient with Hodgkin's Lymphoma

Keimyung Medical Journal 1996;15(3):263-268.

Disseminated Herpes Zoster in Patient with Hodgkin's Lymphoma

호지킨씨 림프종 환자에서 발생한 Disseminated Herpes Zoster 1례

구본식; 이규석; 권호준; 송홍석; 공득수; 허규찬; 송준영

Abstract

Herpes zoster is acute viral infection characterized by vesicular skin lesions which are usually distributed over several unilateral adjacent sensory dermatomes. In about 2% to 6% of cases of zoster; hematogenous dis?semination of virus apparently occursAmong the associated malignancies; hematologic malignancy including Hodgkin's lymphoma; acute lymphocytic leukemia; and immunocompromised patient were frequently associated. We described the clinical manifestation of disseminated herpes zoster in patient with Hodgkin's lymphoma. A 15-years-old male patient was presented with painful grouped visicles on an erythematous base on left temporal head; right back; and right forearm. Tzanck smear revealed multinucleated giant cells; and histopathologic findings were consistent with herpetic infection. Moreover; Herpes Zoster Virus specific 220 kD DNA fragment was detected in PCR performed with vesicular fluid. He was successfully treated by administra?tion of acyclovir without any significant complications. ?

Key Words: Disseminated herpes zoster, Hodgkin's lymphoma, PCR