An Analysis of 1;000
 Consecutive Native Kidney Biopsies

Keimyung Medical Journal 1996;15(2):126-134.

An Analysis of 1;000 Consecutive Native Kidney Biopsies

성인 신생검 1000례에 대한 분석

박용일; 이성문; 김현철; 석준; 장국진; 박관규; 손철호; 박성배; 이태희

Abstract

We performed 1;000 consecutive native kidney biopsies using the 14 gauge Franklin-modified Vim-Silverman needle in adults at Keimyung University Hospital between Dec 1978 and Aug 1994 to assess the knowledge regarding renal histology on patient management. The indications for renal biopsy were ? nephrotic syndrome (611%); hematuria and proteinuria(171%); glomerulopathy associated with systemic diseases(ll 2%); renal insufficiency(33%); acute glomerulonephritis^ 2%); acute renal failure(2.6%); uremia(l0%) and rapidly pro?gressive glomerulonephritis(0.5%) One core of renal was tissue obtained m 20 7% of the cases; 2 cores in 533% and above 3 cores m 260% The tissue specimen was adequate for histological evaluation in 90 6% of the cases The major glomerular diseases were minimal change nephrotic syndrome(27.8%); Ig A nephropa thy( 173%); focal segmental glomerulosclerosis(l06%); membranous nephropathy(l04%); lupus nephritis(81%); membranous proliferative glomerulonephritis(76%); chronic glomerulonephritis^5%) and crescentic glomeru?lopathy ( 15%) Complications occurred in 518% of the total biopsies performed; consisting of microscopic hematuria lasting for more than 12 hours(383%); gross hematuria(9.0%); pam and tenderness(58%) and perirenal he-matoma^ 7%) Major complications occurred in 12 patients(l 2%) in whom active therapy was required In 7 cases; active hemorrhage developed and transfusion was required Surgical repair of laceration with persistent bleeding was required m two patients Three patients developed arteriovenous fistula following renal biopsies; who were treated successfully with superselective embolization We suggested that a percutaneous renal biopsy is necessary for optimal evaluation of the glomerular disease when it comes to patient management

Key Words: Percuteneous renal biopsy, Adequacy, Complication