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Cucurbitacin E’s Anti-Cancer Effects on HCT116 Human Colon Cancer Cells by Controlling Expression and Phosphorylation levels of Caspase-9, eIF-2α, and ATF-4 |
Anil Kumar Yadav, Byeong-Churl Jang |
Keimyung Med J. 2020;39(1):6-13. Published online June 2, 2020 DOI: https://doi.org/10.46308/kmj.2020.00059 |
Cucurbitacin E’s Anti-Cancer Effects on HCT116 Human Colon Cancer Cells by Controlling Expression and Phosphorylation levels of Caspase-9, eIF-2α, and ATF-4 Upregulated expression of the genes encoding translation initiation factors eIF-4E and eIF-2α in transformed cells Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells Quantitative chemical proteomics reveals anti-cancer targets of Celastrol in HCT116 human colon cancer cells Regulation of Reticulocyte eIF-2α Kinases by Phosphorylation E-CADHERIN EXPRESSION DOWNREGULATION ELEVATES TUMOROGENIC POTENTIAL OF HUMAN COLON CANCER CELL LINE HCT116 VIA INCREASE IN CANCER STEM CELLS AMOUNT Expression of Recombinant Carcinoembryonic-Antigen-Human-β-Defensin-2 Gene in Colon Cancer HCT116 Cells Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells The expression of caspase-9 in colon mucosa, adenoma, cancer and the lentivirus mediated over-expression of it in colon cancer cells Epidermal growth factor expression in human colon and colon carcinomas: Anti-sense epidermal growth factor receptor rna down-regulates the proliferation of human colon cancer cells |