| Role of 3D-CT in Assessment of Pelvic Fracture
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| 골반골절에 있어서 3D-CT의 역할 |
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이성문; 강창수; 신주용; 서수지 |
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| Abstract |
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Purpose： To evaluate the
usefulness of 3D-CT in the assessment of pelvic fracture.
Material & Methods: Consecutive 46 patients with pelvic fracture who investigated by both plain radiography and CT were included in analysis; 13 of 47 patients had pelvice findings led to attempts to correct the deficiency with cholinomimetic agents and those attempts was effective in some patients. However; there have been no pharmacologic agent proved to be successful. Donepezil is the reversible acetylcholine esterase inhibitor with long half-life and high affinity to CNS; and was found to great improvement in cognitive function in clinical trials in Europe and US without compromised hepatotoxicity. The other pathophysiology of AD includes wide range of neuro-transmitter imbalances and cortical atrophy; so that combined treatment approach such as cholinergic/serotonergic dru^ and cholinergicysomatostatinergic drug should be considered.
As a preventive approach; neurotrophic factor; which may delay degenerative process of cholinergic neuron; is clinically valuable when administrated directly into ventricles.
In many cases; amyloid deposits are seen as the distinctive neuropathology of AD; and the presence of amyloid precursor protein gene on chromosome 21 will lead to the gene therapy. As the disease advances; various degrees of neuropsychiatry disturbances become so marked and may be reduced by treatment of associated depression; anxiety; disruptive behaviors; and psychotic symptoms with appropriate psychotropic medications. However; these diugs may make patients confused; requiring reduction or withdrawal of the medication.
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| Key Words:
Pelvis, fractures
Computed Tomography (CT), three- dimensional |
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